Technology
All photos taken from the Clinical Genomics Centre
Fluidigm® Biomark™
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Automated, high-throughput, high performance PCR/qPCR and flow cytometry system, powered by microfluidics technology
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Ideal for projects of scale, allowing for cost advantages
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Capable of various analyses, including flow cytometry, gene expression, genotyping, copy number variant analysis, and PCR
Covaris® Ultrasonicator
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High-throughput ultrasonicator supporting a variety of sample preparation procedures
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Ideal for projects of scale, with capabilities for automation
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Capable of processing up to 96 samples in a single run
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Capable of various processes, including cell lysis, DNA extraction, and shearing of genetic material
Illumina® CBOT
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Automated system that creates clonal clusters from DNA templates
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Prepares samples for sequencing on Illumina HiSeq experiments
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Amplifies cDNA fragments on Illumina flow cells
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Compatible with LIMS (laboratory information management system), allowing efficient sample tracing
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Ideal for sample preparation processes where sequencing using a HiSeq is required
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Automated liquid handling system, with modules allowing for shake, heat, and cooling protocols
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Compatible with up to 384 well plates, allowing high-throughput sample handling and preparation
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Multiple applications, including sample mixing and prep for sequencing, cell disruptions, and immunoassays
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Versatile sample preparation system, with automation for consistent performance across multiple experiments
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Removal of manual steps decreases processing time and chance of error
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Wide range of applications for projects involving the isolation and purification of nucleic acids, proteins, and cells
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Automated workstation with powerful and intelligent liquid handling
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Removal of manual steps promotes workflow automation and decrease in user error
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High-throughput capabilities allow large volumes of samples to be processed simultaneously
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High-throughput multiplex genotyping array and imaging, allowing for population-scale analyses
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Automated processing to reduce hands on-time
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Capable of various analysis types, including human genotyping, cytogenetics, methylation analysis, and more
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Scanning technology paired with Illumina Infinium Assays for powerful multiplex genotyping (see Infinium® Workflow)
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Choice of standardized or customized arrays for a variety of experiments
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Production-scale genotyping arrays for high-throughput experiments
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Arrays are used for various purposes, including:
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The detection of genetic associations with complex traits​
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Fine mapping of quantitative trait loci (QTL)
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Detecting signatures of selection, and implementing genomics selection to farm animal species
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Investigating the relationship between genetics and susceptibility to complex diseases
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Trait and population-focused genotyping of large sample cohorts
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Studying effects of genetic variation on drug absorption, distribution, and metabolism
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Studying markers with genomic regions of interest
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Detecting selection markers, and screening complex genetic traits in plant or animal breeding
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Multi-channel machine for streamlining experiments; seamlessly integrates hybridization, watching, and imaging into a single instrument
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Capable of supporting a wide range of experiments, including genotyping and gene expression profiling
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Compatible with Axiom™ arrays for high-throughput experiments
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Machine combining mass spectrometry and PCR, allowing for accurate and rapid analysis of nucleic acids
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Supports up to 384 well plates for high-throughput experiments
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Wide range of applications, including but not limited to pharmacogenetics, tumor profiling, methylation analysis, and human genotyping
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Efficient, fast, and high-throughput real-time PCR system
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Supports up to 384 well plates
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Capable of a variety of experiments, including but not limited to gene expression analysis and allelic discrimination assays
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Powerful software tools allow automation, reducing hands-on time and user-produced error
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Gold standard Illumina sequencing-by-synthesis machinery
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Short-read paired-end sequencing (2 x 150 bp)
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High quality sequencing for a variety of analyses, including but not limited to whole genome genotyping, genome-wide methylation analysis, and RNA-seq analysis
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Various throughput options and streamlined workflow for fast turnaround for NGS experiments
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Gold standard Illumina sequencing-by-synthesis machinery
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Short-read paired-end sequencing (2 x 300 bp)
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Variety of applications including but not limited to small genome sequencing, targeting gene sequencing, and metagenomic sequencing
